Firefighters responded to a fire at the former Greek Key restaurant in Endicott early Monday morning.
According to the Endicott Fire Department, the blaze broke out around midnight at the building at 113 South Nanticoke Avenue.
The building sustained significant damage from the fire. No injuries have been reported.
The cause of the fire is under investigation.
Firefighters from Endwell, Vestal, West Corners and Union Center also responded to the incident.